Robert hugin net worth3/20/2023 We look forward to launching the psoriasis indication later this quarter following FDA action. Scott will detail many of the metrics that give us the confidence that our team is fully capitalizing on the opportunity of building a new market for this innovative oral compound. team launched Otezla for psoriatic arthritis in April and are making outstanding progress in building the foundation of a first-class launch. Over the next few quarters, we expect significant increased visibility on our next generation of registration track studies.īuilding a market-leading inflammation and immunology franchise is also a key corporate initiative. Mark will outline some of the key studies that are accelerating our impact in the hematology oncology field. In the second half of the year, collaborations are positioned to evaluate Abraxane, Revlimid, CC-486 and other pipeline assets in combination regimens with emerging immuno-oncology therapies. We’re aggressively moving these programs forward with our partners, Acceleron and Agios.ĭuring the first half of the year, our oncology programs were advanced by the initiation of Phase III studies testing Abraxane as an adjutant treatment in patients with surgically resected pancreatic cancer and as maintenance therapy in patients with squamous non-small cell lung cancer. The future of our hematology franchise was further enhanced through meaningful progress on strategic collaborations, including ACE-011 and ACE-536 in beta thalassemia, and exciting data in targeted relapse refractory AML with AG-221. During the quarter, we strengthened our hematology product portfolio with important new clinical data in MDS, AML, and mantle cell lymphoma. We’re making exceptional progress in building for the future. Jacquie and Mark will discuss the results and our outlook in greater depth in a few minutes.Ĭapturing the full value of our franchises is the highest order of corporate priority. This strong performance supports raising our full-year financial guidance. Increased Revlimid duration of therapy and accelerating global launches of pomalidomide and Abraxane in pancreatic cancer fueled substantial volume and revenue growth. The strong revenue and earnings growth reported this morning reflect the excellent operating performance of our teams. Our businesses across functions and geographies have outstanding momentum. Outstanding results produce the resources that allow us to invest in the discovery and development of tomorrow’s transformational therapies, and our teams across the globe are delivering. Operational excellence is the foundation of our business model. I appreciate the opportunity to update you on the excellent results of the quarter and the significant progress achieved advancing strategic corporate initiatives. Thanks Patrick, and thank you everyone for joining us this morning. I would now like to turn the call over to Bob. Finally, a reconciliation of the adjusted financial measures to the most comparable GAAP measures are available as part of the earnings release. These statements speak only as of today’s date and we undertake no duty to update or revise them. A description of these risks can be found in our most recent 10-Q on file with the SEC. These statements are subject to risks and uncertainties that may cause actual results to differ from those forecasted. Joining me in the room today with prepared remarks are Bob Hugin, our Chairman and Chief Executive Officer Jacquie Fouse, our Chief Financial Officer Mark Alles, who is Global Head of our Hematology and Oncology franchise and the Global Head of our Inflammation and Immunology franchise, Scott Smith.Īs a reminder, during today’s call we will be making forward-looking statements regarding our financial outlook in addition to regulatory and product development plans. The press release reporting our financial results in addition to the presentation for today’s webcast can be accessed by going to the Investor Relations section of the corporate website at. Thanks, Nicole, and welcome everyone to our second quarter earnings conference call. I would now like to turn the conference over to Patrick Flanigan, Vice President, Investor Relations at Celgene. I would like to remind you that this call is being recorded. All participants will be in a listen-only mode until the question and answer session at the end of the conference. Good morning and welcome to the Celgene Second Quarter 2014 Earnings conference call.
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Weather, on the other hand, looks splendid, with rain creating streaks on your windows and falling all around in spectacular fashion.Īnother particularly bad graphical element is the trees. Clouds themselves are a particular eyesore, even with the settings turned up. The skybox is an important one for flight simulators, and while X-Plane 11 improves over predecessors, it isn’t the best either. Cities like New York City feature not just accurate buildings, but traffic and road layouts that really add to the experience of a living, breathing world below you. That said, they can quickly become too complex for basic users.Ĭities like New York City feature not just accurate buildings, but traffic and road layouts that really add to the experience of a living, breathing world below you.Īside from the planes themselves, the environments you pick from feel great, with realistic cities properly laid out to their real-world counterparts. The menus in X-Plane 11 have been more streamlined overall versus previous installations of the series, which is a welcome addition. Users also have the ability to fine-tune their aircraft’s specs, with options for weight, fuel level and more, allowing for some interesting setups. The game is definitely more geared for the enthusiast who wants to replicate true to life experiences. These options allow for a good bit of diversity, but there aren’t a ton of cool custom missions aimed at simply having fun as you’d see in FSX (no landing planes on moving buses here). For environments, there are lots of major airports and cities to pick, and you can either select custom weather effects or go with real-world conditions updated in real-time. X-Plane 11 allows you to choose from a limited range of aircraft like basic prop planes to huge jumbo jets (though you can purchase more in the form of DLC). 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This unit is one of the more popular, affordable options, so we’ll briefly discuss how to set it up. There are a number of these to choose from, but we went with the Thrustmaster T16000M FCS HOTAS which includes the added pedals. Combining one of these with X-Plane 11 will increase the immersion considerably. A HOTAS, or “hands-on throttle-and-stick,” is a set of peripherals that allow you to control your in-game aircraft with more realistic inputs. Be sure to adjust the settings in the menu to your specific setup for things like resolution, quality, controls, etc.Īside from setting up your game, it’s a good idea to connect your HOTAS during the initial setup. Once your software is fully set up, you can now launch the game and get yourself flying. While many popular flight simulators are starting to show their age, X-Plane 11 is a breath of fresh air in the genre, and a breathtaking one at that. 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Quoting a translated interview with him from Nintendo Dream in 2003: Only in his 20s, he was already working with other industry greats such as Shigeru Miyamoto and the late Satoru Iwata.īut even at an early part of his career, he felt shackled by previous successes and the looming pressure of creating sequels over trying out original ideas. Sakurai followed up with Kirby’s Adventure for the Famicom in 1993, and it was met with even greater acclaim. On top of the unusual design, the game boasted a new style of gameplay not seen in the past, and it became an instant classic and was HAL’s most successful game at the time. Intended to be a placeholder character, Kirby ended up being loved by the designers to the point where they decided to keep him in the final version. Having joined HAL Laboratory as a game designer straight out of high school, Sakurai’s first project was directing Kirby’s Dreamland for the Game Boy, released in 1992. What do these two video game series have in common? 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